In 1905, in the far North-East corner of South Africa, missionaries from the Church of Scotland started a mission to the Venda and Shangaan people. The need for medical services led to the establishment of the Donald Fraser Hospital in 1933, by Dr RD Aitken. This book traces the story of that mission and the hospital through the turbulent history of South Africa to the present (2020). It describes the move of health care from prescriptive to participatory. It provides biographies of the pioneers and personal experiences of those who lived and worked there. It is a story of the triumph of Christian endeavour.