Left penniless by the death of his improvident father, young Nicholas Nickleby assumes responsibility for his mother and sister and seeks help from his Scrooge-like Uncle Ralph. Instantly disliking Nicholas, Ralph sends him to teach in a school run by the stupidly sadistic Wackford Squeers. Nicholas decides to escape, taking with him the orphan Smike, one of Squeers's most abused young charges, and the two embark on a series of adventurous encounters with an array of humanity's worst and best—greedy fools, corrupt lechers, cheery innocents, and selfless benefactors.